Automated synthesis of backbone protected peptides† †Electronic supplementary information (ESI) available: Synthesis and characterization of peptides, experimental conditions. See DOI: 10.1039/c4cc03065f Click here for additional data file.

Double quick, double click reversible peptide “stapling”† †Electronic supplementary information (ESI) available: Synthesis and characterization, additional biophysical and biochemical analyses. See DOI: 10.1039/c7sc01342f Click here for additional data file. Click here for additional data file. Click here for additional data file.

Synthesis of S peptides......................................................................................................................... 4 WT-S peptide – 8 ................................................................................................................................ 5 OX-S-Cys peptide – 2c ...................................................................................

Artificial disulfide-rich peptide scaffolds with precisely defined disulfide patterns and a minimized number of isomers† †Electronic supplementary information (ESI) available: Experiments on the synthesis and characterization of peptides, the oxidative folding of peptides, and the tryptic digestion LC-MS analysis of disulfide connectivity. See DOI: 10.1039/c6sc05710a Click here for additional data file.

3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters† †Electronic supplementary information (ESI) available: Experimental procedures for the production of 1, all model peptides and proteins and their reactions with MPA including HPLC, LC-MS and NMR characterisation of selected products. See DOI: 10.1039/b815888f Click here for additional data file.

Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions.

AuICl-bound N-heterocyclic carbene ligands form MII4(LAuCl)6 integrally gilded cages† †Electronic supplementary information (ESI) available: Experimental procedures, synthesis and characterization data for subcomponents and cages, and optical, microscopy, ESI-MS and NMR data. CCDC 1061936. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc03065j Click here for additional data file. Click here for additional data file.

Profluorescent verdazyl radicals – synthesis and characterization† †Electronic supplementary information (ESI) available. CCDC 1051008–1051011. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc00724k Click here for additional data file. Click here for additional data file.